Life is hard. And beautiful. Then you die. Trust Jesus.I blog for the persecuted church
Travike
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Name: Isaac
Country: Thailand
Metro: Krung Thep
Birthday: 1/4/1986
Gender: Male


Interests: Waiting for a special friend, preaching, travel, life, work, Bible, people, hiking, nun-chuks, adventure, chalk drawing, sci-fi, machines, knives, HTML/web design... Also, studying lots of stuff. Have been to or through: USA, Canada, Japan, Taiwan, Thailand, Laos, Cambodia, Hong Kong, Singapore, and Malaysia.
Expertise: Being a little different.
Occupation: Preacher, Teacher
Industry: The Gospel of Jesus Christ...


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AIM: TravIke5
MSN: ike27@ekit.com


Member Since: 9/27/2004

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Tuesday, September 09, 2008

Combat in the body

There is no doubt that the environment that we live in is "dirty". Of course, by dirty we mean, filled with the undesirable and harmful. Each day we fight it with antibacterial cleaners, soaps and medicines. The more aware spend countless hours of their lives cleaning their hands and bodies, washing away billions of antigens - bacteria, viruses, protozoa, et ctera. They have an alertness to the thousand-year-old battle that has been going on both within and without the body to "arrest and cure disease," quoting Herlihy(2007).

To understand the body's defense frontlines, one must first understand the components, processes and mechanisms that run and maintain the human immune system. These include the mechanical and chemical barriers, phagocytosis and killer cells, inflammation/fevers, protective proteins and specific immunity. But time and space here does not permit a thorough description of all of these, therefore the focus will be on a few immunity responses - a mosquito bite, a poison ivy reaction, and specific(acquired) immunity.

A lone mosquito finds your arm a tasty treat until your nervous system relates to the brain that there is a cutaneous release of histamine by your mast cells. As soon as you get that message, you look over and slap the irritation. This histamine release is from the mast cells being challenged - in this case by the mosquito's beak and saliva. What actually happens, is that the proteins or polysaccharides within the mosquito's saliva bind with the IgE antibodies, stimulating the mast cells to release various preformed and lipid mediators. The most notable of these chemicals is histamine. Histamine dilates venules, activates the endothelium, and increases blood vessel permeability. What happens next can be seen by the naked eye as swelling, redness and warmth. Of course, the area will itch as well, since all this activity irritates all of the nerve endings nearby, which then tell you to "squash that bug."

Another allergy, known as contact dermititus, can be caused by plants such as poison ivy. This immune system response varies from the previous in that the T-cells are doing the work here. Let's say you brush up against some of that nasty stuff out in the forest. Well, this oil from the plant, called urushiol, rubs off onto your arm. Well, urushiol has an odd property by which it tends to bind to and chemically react with proteins on exposed skin cells. T lymphocytes then begin to attack the affected cells as if those skin cells were not part of the body. The attack is actually directed towards the complexes of urushiol, which since have already reacted with the skin cells, causes swelling, redness, itching, even blisters and vesicles. The good news is, if you don't itch too much or don't have too severe of an allergic reaction, you'll get over it in a week or two. If, perchance, your mast cells release too many of their granules, they may cause massive vasodilation and bronchoconstriction, a severe reaction called anaphylaxis.

Now coming to specific immunity, the body often comes in contact with the same pathogens at various stages in it's life. To protect itself from a recurring illness or attack, our bodies will "remember" those pathogens by means of a specific antibody. We use the word antibody as a simple way to describe immunoglobulins secreted by B lymphocytes. Theses antibodies work by attacking antigen membranes and binding with the antigen, making it much easier for phagocytic cells(including macrophages) to destroy the antigen. They also secrete various complement proteins that facilitate the destruction of pathogens by phagocytes.


Friday, July 18, 2008

2008 Olympics

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Sunday, February 10, 2008

Isaac Mazur's Facebook profile


Thursday, October 11, 2007



Wednesday, August 15, 2007

Changes...

Some have said that it's not a big change, but for me, myself and I, it is.

No, I'm not getting married. Too many people have asked me that since last time I posted.

I'm going to Mahidol University, studying a Bachelor of Science in Biological Science - focus in Biomedicine.

I haven't really studied a lot since I finished high school, 4 years ago, and this will be full-time. Big change.



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